SAN FRANCISCO DEPARTMENT OF PUBLIC HEALTH RELEASES 2025 HIV EPIDEMEOLOGY ANNUAL REPORT

SAN FRANCISCO - The San Francisco Department of Public Health (SFDPH) today released the 2025 HIV Epidemiology Annual Report, providing a detailed overview of HIV trends in the city. In 2025, San Francisco recorded 136 new HIV diagnoses, an 8% decrease from 2024.

“From 545 HIV diagnoses reported in 2006 to 136 in 2025, today’s report shows that San Francisco is moving in the right direction in reducing new HIV infections,” said Director of Health Daniel Tsai. “The ultimate goal is to get to zero HIV infections and there is still work to be done to get us there. SFDPH remains committed to providing a strong network of HIV prevention, treatment, and care services.”

There were 53 new HIV diagnoses among Latine/x persons reported in 2025. This marks a 45% decline from the 97 cases among Latine/x persons reported in 2018, but an increase from 47 in 2024. In 2025, new HIV diagnoses declined among Black/African American, White, and Asian/Pacific Islander persons. Latine/x and Black/ African Americans accounted for 39% and 23% of all new diagnoses respectively, despite representing only 17% and 5% of the City’s population. New diagnoses among Whites accounted for 23%, Asian/Pacific Islanders for 11%, Multi‑race individuals for 2%, and Native Americans for 1%.

“In San Francisco, there has been an overall downward trend in new HIV diagnoses among most racial and ethnic groups since 2016, but we must continue to break down barriers to reduce disparities,” said San Francisco Health Officer Dr. Susan Philip. “It is essential that we continue to collaborate with community, healthcare, and academic partners to meet people where they are and build awareness of all of the effective HIV prevention tools available.”

SFDPH leads several programs and initiatives that build HIV awareness in the community and connect people to testing and prevention services, some of which are highlighted below.

Getting to Zero San Francisco: SFDPH is part of Getting to Zero San Francisco (GTZ-SF), a consortium of over 300 members focused on supporting access to PrEP and other efforts to eliminate new HIV infections, preventable deaths, and HIV stigma and discrimination. GTZ-SF is tracking and addressing equitable roll-out of long-acting injectable medications for HIV prevention and treatment.

San Francisco City Clinic PrEP Program: The SFDPH San Francisco City Clinic (SFCC) provides low-barrier access to PrEP to patients disproportionately impacted by HIV. From 2015 through 2025, PrEP use among men who have sex with men (MSM) without HIV increased from 21% to 74% among SFCC patients 18 years and older who were San Francisco residents. Among this group, the proportion of Latine/x MSM on PrEP increased each year from 19% in 2015 to 78% in 2024. PrEP participation among Black/African Americans increased from 52% in 2024 to 67% in 2025. In addition, since its launch in 2023, SFCC has enrolled 175 patients in injectable PrEP, of whom 54% are Latine/x and 20% are Black/African American.

Health Access Points (HAPs): The SFDPH funded Health Access Points are designed to reduce disparities by providing equity-focused, stigma-free, and low barrier HIV/STI/HCV prevention, care and treatment services. Each HAP is designed to address the specific health needs of priority populations including Black/African Americans and Latine/x. In the HAPs second year of operation (July 2024 – June 2025), the total number of people served increased by 11% and more than 21,000 HIV tests were conducted.

Home-based Testing: To help reduce barriers to HIV/STI testing, SFDPH partners with Take Me Home, a program that allows people to order HIV, STI and HCV tests and have them delivered directly to their home The program is promoted in part by the SFDPH led Have Good Sex campaign that aims to reduce stigma in the Black/African American and Latine/x communities. Over 1,300 testing kits were ordered in 2025.

LATIDOS Conference: In 2026, the SFDPH Community Health Equity & Promotion Branch hosted its second annual LATIDOS Conference, bringing together more than 200 frontline workers, community leaders, and partners for a full day of Spanish language programming with a focus on highlighting current STI and HIV trends in California, and sharing community driven, culturally relevant strategies to reduce health disparities.

SFDPH also manages a robust network of programs to help ensure that people living with HIV get and remain connected with their care, such as LINCS (Linkage, Integration, Navigation and Comprehensive Services), Whole Person Integrated Care, and Zuckerberg San Francisco General Hospital’s Ward 86 POP-UP clinic and HAP, “The Lobby”.

The 2025 HIV Epidemiology Annual Report is produced by the SFDPH Applied Research, Community Health Epidemiology, and Surveillance branch and can be read in full here.