Tools for syphilis management
Find resources on syphilis screening, evaluation, treatment, patient education, and how to consult.Contact City Clinic for help with syphilis
Titer and treatment history
Check syphilis titer and treatment history, to help with testing, staging, and treatment:
- Call: 628-217-6688
- Email: DPH-STIReactorDesk@sfdph.org
Diagnosis and treatment
Get clinical consultation on syphilis diagnosis and treatment:
- Call: 628-217-6677
Report syphilis to DPH
Syphilis must be reported to the Department of Public Health by faxing a CMR:
- Confidential morbidity report (CMR)
- Fax to 628-217-6603
- For questions call: 628-217-6653
Managing syphilis during a Bicillin shortage
Guidance
- SFDPH Health Alert: Penicillin G Benzathine (Bicillin L-A) Voluntary Recall and Shortage (PDF)
- CDC guidance on priority actions following the recall
- CDC STI Treatment Guidelines for Syphilis
- CDPH: Alternative therapies for the treatment of syphilis in non-pregnant adults
Medication acquisition
Shortage status updates
Call us at (628) 217-6677. We can help troubleshoot.
Syphilis screening recommendations
California Department of Public Health (CDPH) Updates Syphilis Screening Recommendations
Published October 14, 2024 by the California Department of Public Health
Health Update: Expanded Syphilis Screening Recommendations and Resolution of Benzathine Penicillin G Shortage (PDF)
Published January 23, 2025 by the San Francisco Department of Public Health
Evaluating and treating syphilis
Syphilis: A Review (JAMA)
2025 review of syphilis by experts at City Clinic and California Prevention and Training Center
Prenatal Syphilis Screening, Staging, and Management for Congenital Syphilis Prevention (PDF)
Pocket card by the California Department of Public Health
Evaluating patients for primary syphilis (PDF)
Evaluation algorithm and guide by the California Prevention Training Center
Evaluating patients for secondary syphilis (PDF)
Evaluation algorithm and guide by the California Prevention Training Center
Patient education tools
"That rash or sore might be syphilis" (PDF)
Printable poster created by the San Francisco Department of Public Health
Congenital syphilis FAQ: English (PDF)
Printable handout created by the San Francisco Department of Public Health
Congenital syphilis FAQ: Spanish (PDF)
Printable handout created by the San Francisco Department of Public Health
Congenital syphilis resources from the California Department of Public Health
Resources for providers and patients
Read our congenital syphilis strategic plan
Eliminating Congenital Syphilis in San Francisco, 2024-2027 Strategic Plan
More sexual health resources for providers
Learn about disease reporting in SF, find clinical guidelines and toolkits, sign up for health alerts, and see epidemiological data and reports.See more resources for providersAbout
San Francisco City Clinic is a trusted source for sexual health services and information, known for our experienced professionals and our commitment to delivering compassionate, high-quality care for over 100 years.
Our mission is to improve our community’s sexual health by preventing, diagnosing, and treating sexually transmitted infections (STIs) and HIV, and preventing unintended pregnancy.
Find all City Clinic services and information
Contact information
Address
San Francisco, CA 94102
Monday, Wednesday, Friday
8:00 am to 4:00 pm
Tuesday
1:00 pm to 6:00 pm
Thursday
8:00 am to 11:00 am
1:00 pm to 4:00 pm
Walk-ins may end earlier for some services.
We are closed weekends and holidays.
Phone
Additional info
Medical leadership
Oliver Bacon, MD, MPH: 628-217-6658
Medical Director, City Clinic
San Francisco Department of Public Health
Franco Chevalier, MD, MPH: 628-217-6605
Deputy Medical Director, City Clinic
San Francisco Department of Public Health
Stephanie Cohen, MD, MPH: 628-217-6674
Director, STI/HIV Branch
Population Health Division
San Francisco Department of Public Health
Julia Janssen, MD: 628-217-6074
Deputy Director, STI/HIV Branch
Population Health Division
San Francisco Department of Public Health