Test Order Name - Sin Nombre Virus (Hanta Virus Pulmonary Syndrome) - Serology
Synonym(s) - Hanta Virus Serology, Sin Nombre Virus, Hanta Virus Pulmonary Syndrome Serology
Methodology - EIA: IgG and IgM (LDT/CDC)(Non-Diagnostic)
Acceptable Specimen Type(s) for Testing -
Human specimens:
- Serum:
- Plain Red-Top Tubes: Serum collected in plain, red-top tubes must be separated and transferred to sterile, screw-cap tubes for storage and transport.
- Serum Separator Tubes (SST): SST may be transported after centrifugation.
- Plasma: Plasma may be separated from (specify anticoagulant type) whole blood and transferred to sterile, screw-cap tubes for storage and transport.
- Whole blood: EDTA (lavender top) tubes
Additional specimens may be tested if patient is deceased (Surveillance Use Only) please contact VRDL’s Medical and Epidemiology Liaisons at (510) 307-8585 or VRDL.Submittal@cdph.ca.gov for more information.
Transport / Collection Medium - Not Applicable
Storage and Preservation of Specimen -
- Separated Serum: Refrigerate or freeze separated serum promptly after collection.
- Serum Separator Tubes: Refrigerate, do not freeze.
- Plasma: Refrigerate or freeze separated plasma promptly after collection.
- Whole Blood: Refrigerate, do not freeze.
Ship refrigerated specimens to VRDL on cold packs. Ship frozen specimens to VRDL on dry ice.
Minimum Volume Required -
- Serum: 1 milliliters
- Plasma: 1 milliliters
- Whole Blood in EDTA tubes: 5 milliliters
Additional Collection Instructions -
Prior to submittal please contact the San Francisco Communicable Disease Control Unit (CDCU) for approval: (628) 217-6100
Please submit the Hantavirus Submittal Instructions and Case Report Form (PDF) to VRDL’s Medical and Epidemiology Liaisons at VRDL.Submittal@cdph.ca.gov for pre-approval.
Submit specimens accompanied with both:
- A hard copy of the Hantavirus Submittal Instructions and Case Report Form (PDF)
- A hard copy of the completed VRDL General Purpose Specimen Submittal Form (PDF) or a form generated in the VRDL Lab Web Portal.
Additional Required Information -
Contact VRDL’s Medical and Epidemiology Liaisons at (510) 307-8585 or VRDL.Submittal@cdph.ca.gov for requested supplemental information, including but not limited to animal or environmental exposure, disease onset date, clinical symptoms
Each specimen tube must be labeled with at least two unique patient identifiers, e.g., patient full name and date of birth.
Since the incidence of HPS is rare in California, we recommend that you also submit a respiratory specimen for viral isolation and/or respiratory PCR assays to test for other agents that may be causing your patient’s illness. Please contact VRDL’s Medical and Epidemiology Liaisons at (510) 307-8585 for more information. This does not apply for submissions outside of California.
Send Out? - Yes
Turnaround Time - 10 Business Days
Testing Restrictions -Limitations / Notes / Disclaimer -
Positive result does not confirm infection, clinical correlation is required. Negative result does not preclude the possibility of infection.
Marginal values are likely to represent a patient in the early stages of a response or previously infected with a related, cross-reacting virus or noise in the system
Bacterial or fungal contamination renders the specimen unsuitable for testing.